GPC3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53438-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53438-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53438-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53438-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GPC3
Background:
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human GPC3
Purification method:
Antigen affinity purification
Target Synonym:
DGSX;Glypican proteoglycan 3;Glypican-3 [Precursor];Gpc3;GPC3;GTR2 2;GTR2-2;Heparan sulphate proteoglycan;Intestinal protein OCI 5;Intestinal protein OCI-5;MXR7;OCI 5;OCI-5;OCI5;SDYS;Secreted glypican-3;SGB;SGBS;SGBS1
UNIProt ID:
P51654