MAFA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53394-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53394-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53394-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53394-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MAFA
Background:
Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
37 kDa
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human MAFA
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
HMafA;Mafa;MAFA;Pancreatic beta cell specific transcriptional activator;Pancreatic beta-cell-specific transcriptional activator;RIPE3b1;Transcription factor MafA;Transcription factor RIPE3b1;v maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian);v maf musculoaponeurotic fibrosarcoma oncogene homolog A;V-maf musculoaponeurotic fibrosarcoma oncogene homolog A
UNIProt ID:
Q8NHW3