XPC Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53352-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53352-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53352-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53352-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
XPC
Background:
The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.66 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human XPC
Purification method:
Antigen affinity purification
Target Synonym:
DNA repair protein complementing XP C cells;DNA repair protein complementing XP-C cells;DNA repair protein complementing XPC cells ;p125;RAD4;Xeroderma pigmentosum complementation group C;Xeroderma pigmentosum group C complementing protein;Xeroderma pigmentosum group C protein;Xeroderma pigmentosum group C-complementing protein;Xeroderma pigmentosum group III;XP 3;XP C;XP group C;XP3;Xpc;XPC gene;XPC;XPCC
UNIProt ID:
Q01831