CLK2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53303-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53303-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53303-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53303-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CLK2
Background:
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human CLK2
Purification method:
Antigen affinity purification
Target Synonym:
CDC like kinase 2;CDC-like kinase 2;CLK 2;CLK kinase;CLK2;Clk2 Scamp3;CLK2;Dual specificity protein kinase CLK2;hCLK 2;hCLK2;Tu52
UNIProt ID:
P49760