PSCA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53288-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53288-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53288-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53288-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PSCA
Background:
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
13 kDa
Concentration:
0.78 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:20-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human PSCA
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
PRO 232;PRO232;Prostate stem cell antigen
UNIProt ID:
O43653