MCAM Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53284-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53284-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53284-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53284-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MCAM
Background:
CD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
72 kDa
Concentration:
1.14 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human MCAM
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
A32 antigen;CD 146;CD146;CD146 antigen;Cell surface glycoprotein MUC18;Cell surface glycoprotein P1H12;Gicerin;Mcam;Melanoma adhesion molecule;Melanoma associated antigen A32;Melanoma associated antigen MUC18;Melanoma associated glycoprotein MUC18;Melanoma cell adhesion molecule;Melanoma-associated antigen A32;Melanoma-associated antigen MUC18;MelCAM;MUC 18;MUC18;MUC18;S endo 1;S endo 1 endothelial associated antigen;S-endo 1 endothelial-associated antigen
UNIProt ID:
P43121