TCF7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53275-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53275-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53275-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53275-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
TCF7
Background:
This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.78 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human TCF7
Purification method:
Antigen affinity purification
Target Synonym:
FLJ36364;MGC47735;OTTHUMP00000159391;T cell factor 1;T cell specific transcription factor 1;T-cell factor 1;T-cell-specific transcription factor 1;TCF-1;TCF-7;TCF1;Tcf7;TCF7 transcription factor 7;TCF7;Transcription factor 7 (T cell specific HMG box);Transcription factor 7;Transcription factor-7;T-cell specific;Transcription factor-7;T-cell specific;1
UNIProt ID:
P36402