LEPR Polyclonal Antibody

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Elabscience
Product Code: E-AB-53262
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-53262-20uL20uL£125.00
Quantity:
E-AB-53262-60uL60uL£172.00
Quantity:
E-AB-53262-120uL120uL£237.00
Quantity:
E-AB-53262-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of 293T cell lysate using LEPR Polyclonal Antibody at dilution of 1:250
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using LEPR Polyclonal Antibody at dilution of 1:30(?200)
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Western blot analysis of 293T cell lysate using LEPR Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using LEPR Polyclonal Antibody at dilution of 1:30(?200)

Documents

Further Information

Abbreviation:
LEPR
Background:
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
133 kDa
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human LEPR
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
CD 295;CD295;CD295 antigen;Db;Fa;HuB219;LEP R;LEP-R;LEPR;LEPR;LEPRD;Leptin receptor;Leptin receptor fatty;Leptin receptor gene related protein;Leptin receptor precursor;Leptin receptor precursor;OB R gene related protein;OB receptor;OB-R;OB-RGRP;obl;Obr
UNIProt ID:
P48357

References

  • https://onlinelibrary.wiley.com/doi/abs/10.1002/mrd.23342