HNF1A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53258-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53258-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53258-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53258-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
HNF1A
Background:
The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
67 kDa
Concentration:
0.66 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human HNF1A
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Albumin proximal factor;Hepatic nuclear factor 1 alpha;Hepatic nuclear factor 1;Hepatic transcription factor 1 alpha;Hepatic transcription factor 1;Hepatocyte nuclear factor 1-alpha;HNF 1;HNF 1A;HNF-1-alpha;HNF-1A;hnf1a;HNF1A;Interferon production regulator factor;LF B1;LF B1 hepatic nuclear factor;LFB 1;LFB1;LFB1 hepatic nuclear factor;Liver specific transcription factor LF B1;Liver specific transcription factor LFB1;Liver-specific transcription factor LF-B1;Maturity onset diabetes of the young 3;MODY 3;MODY3;TCF 1;TCF-1;TCF1;Transcription factor 1;Transcription factor 1 hepatic
UNIProt ID:
P20823