GFRA1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53255-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53255-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53255-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53255-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GFRA1
Background:
Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
51 kDa
Concentration:
1.92 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human GFRA1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
GDNF family receptor alpha 1;GDNF family receptor alpha-1;GDNF R;GDNF RA;GDNF receptor alpha;GDNF receptor alpha-1;GDNFR alpha 1;GDNFR alpha;GDNFR;GDNFR-alpha-1;GDNFRA;GDNFRalpha;GFR alpha 1;GFR alpha1;GFR-alpha-1;GFRA 1;Gfra1;GFRA1;GFRalpha1;Glial cell line derived neurotrophic factor receptor alpha;GPI linked anchor protein;MGC23045;PI linked cell surface accessory protein;RET 1L;RET ligand 1;RET1L;RETL 1;RETL1;TGF beta related neurotrophic factor receptor 1;TGF-beta-related neurotrophic factor receptor 1;TRNR 1;TRNR1
UNIProt ID:
P56159