BECN1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-53242
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-53242-20uL20uL£125.00
Quantity:
E-AB-53242-60uL60uL£172.00
Quantity:
E-AB-53242-120uL120uL£237.00
Quantity:
E-AB-53242-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using BECN1 Polyclonal Antibody at dilution of 1:30(?200)
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Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using BECN1 Polyclonal Antibody at dilution of 1:30(?200)

Documents

Further Information

Abbreviation:
BECN1
Background:
Beclin-1 (BECN1), also known as ATG6 or VPS30, has a central role in autophagy, a process of programmed cell survival, which is increased during periods of cell stress and extinguished during the cell cycle. Beclin-1, may play a role in antiviral host defense. It protects against infection by a neurovirulent strain of Sindbis virus. Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. A progressively reduced Beclin-1 expression is reported to correlate with the primary tumor growth of squamous cell carcinoma and adenocarcinoma of the lung. Caspase-mediated cleavage of Beclin 1 promotes crosstalk between apoptosis and autophagy.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
52 kDa
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000
Immunogen:
Synthetic peptide of human BECN1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;Becn1;BECN1;Coiled coil myosin like BCL2 interacting protein;Coiled-coil myosin-like BCL2-interacting protein;GT197;Protein GT197;VPS 30;VPS30
UNIProt ID:
Q14457

References

  • https://www.sciencedirect.com/science/article/pii/S0020138322006258
  • https://www.tandfonline.com/doi/abs/10.1080/01616412.2022.2159109