VGLL1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53198-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53198-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53198-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53198-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
VGLL1
Background:
The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
29 kDa
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:2000-1:10000 ELISA 1:2000-1:20000
Immunogen:
Synthetic peptide of human VGLL1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
Protein TONDU;TDU;TONDU;Transcription cofactor vestigial like protein 1;Transcription cofactor vestigial-like protein 1;Vestigial like 1;vestigial like 1 homolog (Drosophila);Vgl-1;VGL1;Vgll1;VGLL1
UNIProt ID:
Q99990