PTPA Polyclonal Antibody

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Elabscience
Product Code: E-AB-53148
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-53148-20uL20uL£125.00
Quantity:
E-AB-53148-60uL60uL£172.00
Quantity:
E-AB-53148-120uL120uL£237.00
Quantity:
E-AB-53148-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PTPA Polyclonal Antibody at dilution of 1:60(?200)
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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PTPA Polyclonal Antibody at dilution of 1:60(?200)
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Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PTPA Polyclonal Antibody at dilution of 1:60(?200)
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PTPA Polyclonal Antibody at dilution of 1:60(?200)

Documents

Further Information

Abbreviation:
PTPA
Background:
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.08 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PTPA
Purification method:
Antigen affinity purification
Target Synonym:
subunit B'';KIAA0044 ;MGC2184 ;Phosphotyrosyl phosphatase activator;PP2A;PP2A phosphatase activator ;PP2A subunit B';PP2A subunit B' isoform PR53;PP2A subunit B' PR53 isoform ;PPP2R4;PR53 ;PR53 isoform;Protein phosphatase 2; regulatory subunit B-prime;Protein phosphatase 2A activator regulatory subunit 4;Protein phosphatase 2A regulatory subunit B' (PR 53);PTPA;PTPA;Serine/threonine protein phosphatase 2A regulatory subunit B' ;Serine/threonine-protein phosphatase 2A activator;Serine/threonine-protein phosphatase 2A regulatory subunit 4;Serine/threonine-protein phosphatase 2A regulatory subunit B''
UNIProt ID:
Q15257