FBXO8 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53145-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53145-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53145-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53145-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
FBXO8
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.72 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human FBXO8
Purification method:
Antigen affinity purification
Target Synonym:
DC10;F box only protein 8;F box protein 8;F box protein Fbx8;F box/SEC7 protein FBS ;F-box only protein 8;F-box/SEC7 protein FBS;FBS;FBX8;FBX8;FBXO 8;Fbxo8
UNIProt ID:
Q9NRD0