HORMAD2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-53135-20uL | 20uL | £125.00 |
Quantity:
| E-AB-53135-60uL | 60uL | £172.00 |
Quantity:
| E-AB-53135-120uL | 120uL | £237.00 |
Quantity:
| E-AB-53135-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
HORMAD2
Background:
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human HORMAD2
Purification method:
Antigen affinity purification
Target Synonym:
4930529M09Rik;CT46.2;HORM2;HORMA domain containing 2;HORMA domain-containing protein 2;Hormad2;MGC26710;RP23-329P17.4
UNIProt ID:
Q8N7B1