CNOT7 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-53112-20uL | 20uL | £125.00 |
Quantity:
E-AB-53112-60uL | 60uL | £172.00 |
Quantity:
E-AB-53112-120uL | 120uL | £237.00 |
Quantity:
E-AB-53112-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
CNOT7
Background:
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.CNOT7 (CCR4-NOT Transcription Complex Subunit 7) is a Protein Coding gene. Among its related pathways are Deadenylation-dependent mRNA decay and Gene Expression. GO annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is CNOT8.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human CNOT7
Purification method:
Antigen affinity purification
Target Synonym:
BTG1 binding factor 1;BTG1-binding factor 1;CAF 1;CAF-1;CAF1;Carbon catabolite repressor protein (CCR4) associative factor 1;CCR4 associated factor 1;CCR4 NOT transcription complex subunit 7;CCR4-associated factor 1;CCR4-NOT transcription complex subunit 7;CNOT 7;Cnot7;CNOT7;hCAF 1;hCAF1
UNIProt ID:
Q9UIV1