DNAJA4 Polyclonal Antibody

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Elabscience
Product Code: E-AB-53105
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-53105-20uL20uL£125.00
Quantity:
E-AB-53105-60uL60uL£172.00
Quantity:
E-AB-53105-120uL120uL£237.00
Quantity:
E-AB-53105-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DNAJA4 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using DNAJA4 Polyclonal Antibody at dilution of 1:50(?200)

Documents

Further Information

Abbreviation:
DNAJA4
Background:
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJA4 (DnaJ homolog subfamily A member 4) is a SREBP-regulated chaperone that is thought to regulate the cholesterol biosynthesis pathway.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
45 kDa
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human DNAJA4
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
DnaJ (Hsp40) homolog subfamily A member 4;DnaJ (Hsp40) homolog; subfamily A; member4;DNAJ A4;DnaJ heat shock protein family (Hsp40) member A4;DnaJ homolog subfamily A member 4;DNAJA 4;DNAJA4;DNJA4;MST104;MSTP104;PRO1472
UNIProt ID:
Q8WW22