MRPL22 Polyclonal Antibody

Elabscience
Product Code: E-AB-53083
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-53083-20uL20uL£125.00
Quantity:
E-AB-53083-60uL60uL£172.00
Quantity:
E-AB-53083-120uL120uL£237.00
Quantity:
E-AB-53083-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Western blot analysis of Jurkat cell Mouse kidney tissue HepG2 cell lysates  using MRPL22 Polyclonal Antibody at dilution of 1:800
2 / 2
Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using MRPL22 Polyclonal Antibody at dilution of 1:60(?200)

Western blot analysis of Jurkat cell Mouse kidney tissue HepG2 cell lysates  using MRPL22 Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human liver cancer tissue  using MRPL22 Polyclonal Antibody at dilution of 1:60(?200)

Documents

Further Information

Abbreviation:
MRPL22
Background:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L22 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 4q. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
24 kDa
Concentration:
1.02 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human MRPL22
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
MRPL22;39S ribosomal protein L22;39S ribosomal protein L22 mitochondrial precursor;39S ribosomal protein L25;39S ribosomal protein L25; mitochondrial;E030011D16Rik;HSPC158;L22mt;L25mt;mitochondrial;mitochondrial ribosomal protein L22;MRP L22;MRP L25;MRP-L22;MRP-L25;Mrpl22;RM22;RPML25
UNIProt ID:
Q9NWU5