KPNA2 Polyclonal Antibody

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Elabscience
Product Code: E-AB-52984
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52984-20uL20uL£125.00
Quantity:
E-AB-52984-60uL60uL£172.00
Quantity:
E-AB-52984-120uL120uL£237.00
Quantity:
E-AB-52984-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using KPNA2 Polyclonal Antibody at dilution of 1:60(?200)
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using KPNA2 Polyclonal Antibody at dilution of 1:60(?200)

Documents

Further Information

Abbreviation:
KPNA2
Background:
The import of proteins into the nucleus is a process that involves at least 2 steps. The first is an energy-independent docking of the protein to the nuclear envelope and the second is an energy-dependent translocation through the nuclear pore complex. Imported proteins require a nuclear localization sequence (NLS) which generally consists of a short region of basic amino acids or 2 such regions spaced about 10 amino acids apart. Proteins involved in the first step of nuclear import have been identified in different systems. These include the Xenopus protein importin and its yeast homolog, SRP1 (a suppressor of certain temperature-sensitive mutations of RNA polymerase I in Saccharomyces cerevisiae), which bind to the NLS. KPNA2 protein interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.08 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human KPNA2
Purification method:
Antigen affinity purification
Target Synonym:
IMA1;Importin alpha 1;Importin alpha 2;Importin alpha 2 subunit;Importin alpha P1;Importin subunit alpha-1;IPO A1;IPOA 1;IPOA1;Karyopherin alpha 2;Karyopherin alpha 2 RAG cohort 1;Karyopherin alpha 2 subunit;Karyopherin subunit alpha-2;KPNA2;KPNA2 protein;Pendulin;QIP 2;QIP2;RAG cohort 1;RAG cohort protein 1;RCH 1;RCH1;SRP 1;SRP1 alpha;SRP1;SRP1-alpha;SRP1alpha
UNIProt ID:
P52292