FDPS Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52941-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52941-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52941-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52941-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
FDPS
Background:
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.08 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human FDPS
Purification method:
Antigen affinity purification
Target Synonym:
Dimethylallyltranstransferase;Farnesyl diphosphate synthase;Farnesyl diphosphate synthetase;Farnesyl pyrophosphate synthase;Farnesyl pyrophosphate synthetase;Fdps;FPP synthase;FPP synthetase;FPPS;FPPS_HUMAN;FPS;Geranyltranstransferase
UNIProt ID:
P14324