PDHA1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52930-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52930-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52930-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52930-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PDHA1
Background:
PDHA1(Pyruvate dehydrogenase E1 component subunit alpha,somatic form,mitochondrial) is also named as PHE1A.It is one of the 3 enzymes of the pyruvate dehydrogenase complex which is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA.It has 4 isoforms produced by alternative splicing.Defects in PDHA1 are a cause of pyruvate dehydrogenase E1-alpha deficiency (PDHAD) and X-linked Leigh syndrome (X-LS).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
43 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PDHA1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
ODPA;PDH;PDHA;PDHA1;PDHCE1A;PDHE1 A type I;PDHE1-A type I;PHE1A;Pyruvate Dehydrogenase (lipoamide) alpha 1;Pyruvate dehydrogenase complex;E1 alpha polypeptide 1;Pyruvate Dehydrogenase E1 alpha;Pyruvate dehydrogenase E1 component subunit alpha;somatic form;mitochondrial
UNIProt ID:
P08559
References
- https://www.sciencedirect.com/science/article/pii/S0044848621015210