ELF3 Polyclonal Antibody

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Elabscience
Product Code: E-AB-52915
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52915-20uL20uL£125.00
Quantity:
E-AB-52915-60uL60uL£172.00
Quantity:
E-AB-52915-120uL120uL£237.00
Quantity:
E-AB-52915-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ELF3 Polyclonal Antibody at dilution of 1:60(?200)
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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ELF3 Polyclonal Antibody at dilution of 1:60(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ELF3 Polyclonal Antibody at dilution of 1:60(?200)
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using ELF3 Polyclonal Antibody at dilution of 1:60(?200)

Documents

Further Information

Abbreviation:
ELF3
Background:
Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.02 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ELF3
Purification method:
Antigen affinity purification
Target Synonym:
E74 like factor 3;E74 like factor 3 ets domain transcription factor;E74 like factor 3 ets domain transcription factor epithelial specific;E74 like factor 3 ETS domain transcription factor serine box epithelial specific;E74-like factor 3;Elf3;ELF3;Epithelial restricted with serine box ;Epithelial-restricted with serine box;Epithelium restricted Ets protein ESX;Epithelium specific Ets factor 1;Epithelium specific Ets transcription factor 1;Epithelium-restricted Ets protein ESX;Epithelium-specific Ets transcription factor 1;EPR 1;EPR1;ERT;ESE-1;ESX;Ets domain transcription factor serine box;Ets domain transcription factor serine box epithelial specific;Ets transcription factor;ETS-related transcription factor Elf-3;jen;MGC139318
UNIProt ID:
P78545