DUSP7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52886-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52886-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52886-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52886-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
DUSP7
Background:
Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947)-like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.66 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human DUSP7
Purification method:
Antigen affinity purification
Target Synonym:
Dual specificity phosphatase 7;Dual specificity protein phosphatase 7;Dual specificity protein phosphatase PYST2;DUS7;Dusp7;Jnk Stimulatory Phosphatase 1;JSP1;MAP kinase phosphatase X;MKPX;PYST2
UNIProt ID:
Q16829