JPT1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52818-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52818-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52818-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52818-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
JPT1
Background:
Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408).
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.66 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human JPT1
Purification method:
Antigen affinity purification
Target Synonym:
Androgen regulated protein 2;Androgen-regulated protein 2;ARM2;Hematological and neurological expressed 1;Hematological and neurological expressed 1 protein;HN1;HN1;HN1A
UNIProt ID:
Q9UK76