RFX6 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52780-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52780-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52780-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52780-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
RFX6
Background:
The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human RFX6
Purification method:
Antigen affinity purification
Target Synonym:
DNA binding protein RFX6 ;Regulatory factor X domain containing protein 1;RFX6;RFX6 regulatory factor X; 6
UNIProt ID:
Q8HWS3