PSMD12 Polyclonal Antibody

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Elabscience
Product Code: E-AB-52752
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52752-20uL20uL£125.00
Quantity:
E-AB-52752-60uL60uL£172.00
Quantity:
E-AB-52752-120uL120uL£237.00
Quantity:
E-AB-52752-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human tonsil tissue using PSMD12 Polyclonal Antibody at dilution of 1:50(?200)
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Immunohistochemistry of paraffin-embedded Human tonsil tissue using PSMD12 Polyclonal Antibody at dilution of 1:50(?200)

Documents

Further Information

Abbreviation:
PSMD12
Background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
53 kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PSMD12
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
26S proteasome non-ATPase regulatory subunit 12;26S proteasome regulatory subunit p55;26S proteasome regulatory subunit RPN5;MGC75406;p55;proteasome (prosome;macropain) 26S subunit;non ATPase12;Proteasome 26S non ATPase subunit 12 isoform 2;PSD12;PSMD12;Rpn5
UNIProt ID:
O00232