ADRM1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52740-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52740-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52740-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52740-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ADRM1
Background:
The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.54 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ADRM1
Purification method:
Antigen affinity purification
Target Synonym:
110 kDa cell membrane glycoprotein;adhesion regulating molecule 1;Adhesion-regulating molecule 1;ADRM 1;Adrm1;ADRM1;ARM 1;ARM-1;ARM1;Gp110;hRpn13;M(r) 110;000 surface antigen;Proteasomal ubiquitin receptor ADRM1;proteasome regulatory particle non ATPase 13;Proteasome regulatory particle non-ATPase 13;Regulatory particle non ATPase 13;Rpn13;Rpn13 homolog
UNIProt ID:
Q16186