HBG1/HBG2 Polyclonal Antibody

Elabscience
Product Code: E-AB-52690
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52690-20uL20uL£125.00
Quantity:
E-AB-52690-60uL60uL£172.00
Quantity:
E-AB-52690-120uL120uL£237.00
Quantity:
E-AB-52690-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using HBG1:HBG2 Polyclonal Antibody at dilution of 1:100(?200)

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue  using HBG1:HBG2 Polyclonal Antibody at dilution of 1:100(?200)

Documents

Further Information

Abbreviation:
HBG1/HBG2
Background:
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
16 kDa
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human HBG1/HBG2
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
A gamma globin;G gamma globin;Gamma 1 globin;Gamma 2 globin;Gamma A hemoglobin;Gamma globin;Hb F Agamma;Hb F Ggamma;hbfagamma;hbfggamma;HBG 1;HBG 2;HBG1;HBG2;HBGA;HBGR;Hemoglobin gamma 1 chain ;Hemoglobin gamma 2 chain ;Hemoglobin gamma A;Hemoglobin gamma A chain ;Hemoglobin gamma G;Hemoglobin gamma G chain ;Hemoglobin gamma regulator of;Hemoglobin subunit gamma 1;Hemoglobin subunit gamma 2;HSGGL 1;HSGGL1;Methemoglobin;PRO 2979;PRO2979
UNIProt ID:
P69891,P69892