SAA1 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-52681-20uL | 20uL | £125.00 |
Quantity:
E-AB-52681-60uL | 60uL | £172.00 |
Quantity:
E-AB-52681-120uL | 120uL | £237.00 |
Quantity:
E-AB-52681-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
SAA1
Background:
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. SAA1 (Serum Amyloid A1) is a Protein Coding gene. Diseases associated with SAA1 include Amyloidosis Aa and Splenic Artery Aneurysm. Among its related pathways are Peptide ligand-binding receptors and Activated TLR4 signalling. GO annotations related to this gene include heparin binding and chemoattractant activity. An important paralog of this gene is SAA2.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human SAA1
Purification method:
Antigen affinity purification
Target Synonym:
amyloid A;serum;Amyloid fibril protein AA;Amyloid protein A;MGC111216;PIG4;SAA;SAA2;Serum amyloid A protein;serum amyloid A-1 protein;serum amyloid A1;TP53I4;Tumor protein p53 inducible protein 4
UNIProt ID:
P0DJI8