MGP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52676-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52676-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52676-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52676-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MGP
Background:
Matrix Gla protein (MGP) is is a vitamin K-dependent,extracellular matrix protein. MGP plays a pivotal role in preventing soft tissue calcification and local mineralization of the vascular wall. Vitamin K deficiency leads to inactive uncarboxylated MGP (ucMGP),which accumulates at sites of arterial calcification. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. Defects in MGP are the cause of Keutel syndrome (KS),which is an autosomal recessive disorder characterized by abnormal cartilage calcification,peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human MGP
Purification method:
Antigen affinity purification
Target Synonym:
Cell growth inhibiting gene 36 protein;Cell growth-inhibiting gene 36 protein;GAMMA-CARBOXYGLUTAMIC ACID PROTEIN;MATRIX;GIG36;Matrix Gla protein;MGLAP;MGP;MGP;NTI
UNIProt ID:
P08493