STX5 Polyclonal Antibody

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Elabscience
Product Code: E-AB-52597
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52597-20uL20uL£125.00
Quantity:
E-AB-52597-60uL60uL£172.00
Quantity:
E-AB-52597-120uL120uL£237.00
Quantity:
E-AB-52597-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of HepG2 A431 and Raji cell lysates using STX5 Polyclonal Antibody at dilution of 1:1000
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Immunohistochemistry of paraffin-embedded Human liver cancer tissue using STX5 Polyclonal Antibody at dilution of 1:70(?200)
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Western blot analysis of HepG2 A431 and Raji cell lysates using STX5 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using STX5 Polyclonal Antibody at dilution of 1:70(?200)

Documents

Further Information

Abbreviation:
STX5
Background:
The membrane protein syntaxin 5 (STX5) is a key component of soluble N-ethylmaleimide-sensitive factor attachment protein (SNAP) receptor (SNARE) complexes that regulate cellular protein transport, vesicle docking, and membrane fusion. Syntaxin 5 protein is found as a 42 kDa ("long") protein localized to the Golgi complex and endoplasmic reticulum, and a ?short? 35 kDa isoform localized primarily to the Golgi. Formation of the syntaxin 5 SNARE complex, which also includes proteins Sec22B, Bet1, GOSR1, GOSR2, and Ykt6, allows for regulation of ER-to-Golgi transport, intra-Golgi transport, and endosome-to-Golgi retrograde transport. Research studies indicate that the syntaxin 5 SNARE complex also plays an essential role in autophagy following autophagosome formation. Intracellular protein transport mediated by the syntaxin 5 complex is required for transport and localized activity of lysosomal proteases. The experimental reduction or deletion of syntaxin 5 complex components results in non-functional lysosomes and accumulation of autophagosomes.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
40 kDa
Concentration:
1.14 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human STX5
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
OTTHUMP00000185028;SED5;STX5;STX5;STX5A;Syntaxin 5;Syntaxin 5A;Syntaxin-5;Syntaxin5;Syntaxin5A
UNIProt ID:
Q13190