ITM2B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52586-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52586-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52586-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52586-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ITM2B
Background:
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
30 kDa
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ITM2B
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
ABRI;ABri/ADan amyloid peptide;BRI 2;BRI;BRI2;BRICD 2B;BRICD2B;BRICHOS domain containing 2B;E25B;E3 16;E3-16;FBD;imBRI2;Immature BRI2;Integral membrane protein 2B;ITM 2B;ITM2B;ITM2B;Protein E25B;RDGCA;Transmembrane protein BRI
UNIProt ID:
Q9Y287