MICU1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-52519
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52519-20uL20uL£125.00
Quantity:
E-AB-52519-60uL60uL£172.00
Quantity:
E-AB-52519-120uL120uL£237.00
Quantity:
E-AB-52519-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using MICU1 Polyclonal Antibody at dilution of 1:35(?200)
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Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using MICU1 Polyclonal Antibody at dilution of 1:35(?200)
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Immunohistochemistry of paraffin-embedded Human lung cancer tissue using MICU1 Polyclonal Antibody at dilution of 1:35(?200)
Immunohistochemistry of paraffin-embedded Human prost ate cancer tissue using MICU1 Polyclonal Antibody at dilution of 1:35(?200)

Documents

Further Information

Abbreviation:
MICU1
Background:
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human MICU1
Purification method:
Antigen affinity purification
Target Synonym:
Allergen Hom s 4;ara CALC;atopy related autoantigen;atopy related autoantigen CALC;Atopy-related autoantigen CALC;CALC;calcium binding atopy related autoantigen 1;Calcium uptake protein 1;calcium uptake protein 1;mitochondrial;Calcium-binding atopy-related autoantigen 1;CBARA1;EFHA3;FLJ12684;MICU1;MICU1;mitochondrial;mitochondrial calcium uptake 1;MPXPS
UNIProt ID:
Q9BPX6