IL6ST Polyclonal Antibody

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Elabscience
Product Code: E-AB-52510
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52510-20uL20uL£125.00
Quantity:
E-AB-52510-60uL60uL£172.00
Quantity:
E-AB-52510-120uL120uL£237.00
Quantity:
E-AB-52510-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using IL6ST Polyclonal Antibody at dilution of 1:40(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using IL6ST Polyclonal Antibody at dilution of 1:40(?200)

Documents

Further Information

Abbreviation:
IL6ST
Background:
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human IL6ST
Purification method:
Antigen affinity purification
Target Synonym:
CD130;CD130 antigen;CDw130;gp130;GP130 RAPS;IL 6R beta;IL-6 receptor subunit beta;IL-6R subunit beta;IL-6R-beta;IL-6RB;IL6 ST;IL6RB;IL6ST;Interleukin 6 receptor subunit beta;Interleukin receptor beta chain;Interleukin-6 receptor subunit beta;Interleukin-6 signal transducer;Membrane glycoprotein 130;Membrane glycoprotein gp130;Oncostatin M receptor;Oncostatin M receptor alpha subunit;Oncostatin-M receptor subunit alpha
UNIProt ID:
P40189