C4BPB Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52505-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52505-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52505-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52505-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
C4BPB
Background:
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human C4BPB
Purification method:
Antigen affinity purification
Target Synonym:
C4b binding protein beta chain;C4b-binding protein beta chain;C4BP;C4BPB;C4BPB;Complement component 4 binding protein beta;Complement component 4 binding protein beta chain;Complement component 4-binding protein beta;OTTHUMP00000034288;OTTHUMP00000034289;OTTHUMP00000034375;OTTHUMP0000003474;Proline rich protein;PRP
UNIProt ID:
P20851