SPRTN Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52495-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52495-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52495-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52495-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SPRTN
Background:
The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human SPRTN
Purification method:
Antigen affinity purification
Target Synonym:
C1orf124;CA124;Chromosome 1 open reading frame 124 ;DDDL1880;dJ876B10.3;PRO4323;RP5-876B10.3;Spartan;SprT-like domain at the N terminus;SprT-like N-terminal domain;Zinc finger RAD18 domain-containing protein C1orf124
UNIProt ID:
Q9H040