BLNK Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52474-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52474-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52474-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52474-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
BLNK
Background:
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human BLNK
Purification method:
Antigen affinity purification
Target Synonym:
AGM4;B cell adapter containing SH2 domain protein;B cell adapter containing Src homology 2 domain protein;B cell adaptor containing SH2 domain;B cell linker;B cell linker protein;B cell-specific adaptor protein;B-cell activation;B-cell adapter containing a SH2 domain protein;B-cell adapter containing a Src homology 2 domain protein;B-cell linker protein;BASH;Bca;BLNK;BLNK s;BLNK;Cytoplasmic adapter protein;Ly 57;Ly57;Lymphocyte antigen 57;Lyw 57;Lyw57;MGC111051;SH2 domain-containing leukocyte protein;65-KD;SLP 65;SLP-65;SLP65;Src homology [SH2] domain-containing leukocyte protein of 65 kD;Src homology 2 domain containing leukocyte protein of 65 kDa;Src homology 2 domain-containing leukocyte protein of 65 kDa
UNIProt ID:
Q8WV28