UMPS Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52440-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52440-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52440-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52440-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
UMPS
Background:
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
52 kDa
Concentration:
0.7 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human UMPS
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
ODC;OMPdecase;OPRT;OPRTase;Orotate phosphoribosyl transferase and orotidine 5' decarboxylase;Orotate phosphoribosyltransferase;Orotate phosphoribosyltransferase phosphoribosyltransferase;Orotidine 5' phosphate decarboxylase;Orotidine 5''-phosphate decarboxylase;RP11-71H17.9;UMP synthase;Umps;UMPS;Uridine 5' monophosphate synthase;Uridine monophosphate synthetase
UNIProt ID:
P11172