VRK1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52422-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52422-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52422-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52422-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
VRK1
Background:
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
45 kDa
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human VRK1
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
MGC117401;MGC138280;MGC142070;PCH1;PCH1A;Serine/threonine protein kinase VRK1;Serine/threonine-protein kinase VRK1;Vaccinia related kinase 1 ;Vaccinia virus B1R related kinase 1;Vaccinia-related kinase 1;VRK1;VRK1
UNIProt ID:
Q99986