ZNF354A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52385-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52385-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52385-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52385-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ZNF354A
Background:
ZNF354A, also called EZNF, KID-1 or TCF17, belongs to the Kr?ppel C2H2-type zinc-finger family of proteins that contain KRAB domains and act as transcriptional regulators. Expressed primarily in the adult kidney, ZNF354A is a transcriptional repressor that plays a role in late renal development and is suppressed after renal ischemia. The N-terminus of ZNF354A contains the KRAB domain which confers transcriptional repressor activity, while the C-terminus contains multiple Cys2His2-zinc fingers. ZNF354A is located in the nucleolus and is thought to specifically influence development of the proximal tubule by shutting off dispensable or inhibitory genes. Reduced ZNF354A expression prevents proper cell differentiation and may, therefore, be implicated in renal carcinoma.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human ZNF354A
Purification method:
Antigen affinity purification
Target Synonym:
EZNF;HKL1;HLK1;Homo sapiens zinc finger protein 354A;KID 1;KID1;Kidney; ischemia; and developmentally regulated protein 1;Renal transcription factor Kid 1 ;TCF-17;TCF17;Transcription factor 17;Z354A;Zinc finger protein 354A;Zinc finger protein eZNF;ZNF354A
UNIProt ID:
O60765