METTL7A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52354-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52354-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52354-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52354-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
METTL7A
Background:
METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1,100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.6 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human METTL7A
Purification method:
Antigen affinity purification
Target Synonym:
AAM B;AAMB;DKFZP586A0522;MET7A;Methyltransferase like 7A;Methyltransferase-like protein 7A;METTL 7A;METTL7A;METTL7A methlytransferase like 7A;Protein AAM-B;Protein AAMB
UNIProt ID:
Q9H8H3