EDARADD Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52310-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52310-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52310-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52310-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
EDARADD
Background:
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:35-1:200, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
Purification method:
Antigen affinity purification
Target Synonym:
Cr;Crinkled homolog;ectodysplasia A receptor associated death domain;Ectodysplasin-A receptor-associated adapter protein;ED3;EDA3;EDAD;EDAR associated death domain;EDAR-associated death domain protein;EDARADD;Protein crinkled homolog
UNIProt ID:
Q8WWZ3