LRRC19 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52280-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52280-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52280-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52280-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
LRRC19
Background:
LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
42 kDa
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human LRRC19
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
FLJ21302;Leucine rich repeat containing 19;leucine rich repeat containing protein 19;Leucine-rich repeat-containing protein 19;LRC19;LRRC 19;LRRC19
UNIProt ID:
Q9H756