FNDC3B Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52260-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52260-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52260-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52260-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
FNDC3B
Background:
Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:30-1:150, ELISA 1:5000-1:10000
Immunogen:
Full length fusion protein
Purification method:
Antigen affinity purification
Target Synonym:
DKFZp686D14170 ;DKFZp762K137;Factor for adipocyte differentiation 104;FAD104;fibronectin type III domain containing 3B ;FLJ23399;HCV NS5A binding protein 37 ;MGC10002;NS5ABP37;PRO4979;YVTM2421
UNIProt ID:
Q53EP0