SEMA4D Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52208-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52208-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52208-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52208-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
SEMA4D
Background:
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.4 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:300, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human SEMA4D
Purification method:
Antigen affinity purification
Target Synonym:
A8;BB 18;BB18;CD 100;CD100;CD100 antigen;Coll 4;COLL4;Collapsin 4;Collapsin4;GR3;Leukocyte activation antigen CD100;M sema G;MSEMA;SEM4D;Sema 4d;Sema domain immunoglobulin domain Ig transmembrane domain TM and short cytoplasmic domain semaphorin 4D;Sema H;SEMA J;Sema4d;Semacl 2;Semacl2;SemaH;SEMAJ;Semaphorin 4D;Semaphorin C like 2;Semaphorin H;Semaphorin J;Semaphorin-4D;Semaphorin4D;SemaphorinJ;Semcl 2;Semcl2
UNIProt ID:
Q92854