PTPRN Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52202-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52202-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52202-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52202-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PTPRN
Background:
IA-2/PTPRN is a member of the protein tyrosine phosphatase (PTP) family,which contains a transmembrane region,an intracellular PTP-like domain and an extracellular N-terminus. Experiments found that IA-2/PTPRN localizes to secretory granules and is exclusively expressed in neuroendocrine cells (including pancreatic islets cell). IA-2/PTPRNwas found to be a major autoantigen in insulin-dependent diabetes mellitus and the detection of autoantibodies against IA-2/PTPRN is commonly used as a diabetes diagnosis marker.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.96 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PTPRN
Purification method:
Antigen affinity purification
Target Synonym:
CA 512;FLJ16131;IA 2;IA 2/PTP;IA2;IA2/PTP;ICA 3;ICA 512;ICA3;ICA512;Islet cell antigen 2;Islet cell antigen 512;Islet cell autoantigen 3;Protein tyrosine phosphatase like N;Protein tyrosine phosphatase like N precursor;Protein tyrosine phosphatase receptor type N;PTP IA 2;PTP IA-2;PTP IA2;PTPIA 2;PTPN;Ptprn;PTPRN protein;PTPRN;R PTP N;R-PTP-N;Receptor type tyrosine protein phosphatase like N;Receptor-type tyrosine-protein phosphatase-like N;RPTPN
UNIProt ID:
Q16849