PRAME Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52200-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52200-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52200-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52200-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
PRAME
Background:
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:250, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human PRAME
Purification method:
Antigen affinity purification
Target Synonym:
4930534P07Rik;Cancer/testis antigen 130;CT130;MAPE;Melanoma antigen preferentially expressed in tumors;OIP 4;OIP-4;OIP4 ;OPA interacting protein 4;Opa interacting protein OIP4;OPA-interacting protein 4;PRAME;PRAME;Preferentially expressed antigen in melanoma ;Preferentially expressed antigen of melanoma;RP23-250F8.3
UNIProt ID:
P78395