HSD11B1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52192-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52192-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52192-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52192-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
HSD11B1
Background:
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
1.2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human HSD11B1
Purification method:
Antigen affinity purification
Target Synonym:
11 beta HSD 1;11 beta HSD1;11 beta hydroxysteroid dehydrogenase 1;11 DH;11-beta hydroxysteroid dehydrogenase;type 1;11-beta-HSD1;11-beta-hydroxysteroid dehydrogenase 1;11-DH;11DH;Corticosteroid 11 beta dehydrogenase isozyme 1;Corticosteroid 11-beta-dehydrogenase isozyme 1;CORTRD2;DHI1;HDL;HSD 11;HSD11;HSD11B;HSD11B1;HSD11L;Hydroxysteroid (11 beta) dehydrogenase;Hydroxysteroid (11 beta) dehydrogenase 1;MGC13539;SDR26C1;short chain dehydrogenase/reductase family 26C;member 1
UNIProt ID:
P28845