BAP1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-52177
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-52177-20uL20uL£125.00
Quantity:
E-AB-52177-60uL60uL£172.00
Quantity:
E-AB-52177-120uL120uL£237.00
Quantity:
E-AB-52177-200uL200uL£344.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using BAP1 Polyclonal Antibody at dilution of 1:35(?200)
2 / 2
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using BAP1 Polyclonal Antibody at dilution of 1:35(?200)
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Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using BAP1 Polyclonal Antibody at dilution of 1:35(?200)
Immunohistochemistry of paraffin-embedded Human breast cancer tissue using BAP1 Polyclonal Antibody at dilution of 1:35(?200)

Documents

Further Information

Abbreviation:
BAP1
Background:
This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Concentration:
0.8 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:40-1:200, ELISA 1:5000-1:10000
Immunogen:
Fusion protein of human BAP1
Purification method:
Antigen affinity purification
Target Synonym:
BAP 1;Bap1;BAP1;BRCA 1 associated protein 1;BRCA1 associated protein 1;BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase);BRCA1-associated protein 1;Cerebral protein 13;Cerebral protein 6;DKFZp686N04275;FLJ35406;FLJ37180;HUCEP 13;Hucep 6;HUCEP13;Hucep6;KIAA0272;TPDS;Ubiquitin carboxy terminal hydrolase;Ubiquitin carboxyl terminal hydrolase BAP 1;Ubiquitin carboxyl terminal hydrolase BAP1;Ubiquitin carboxyl-terminal hydrolase BAP1;UCHL2
UNIProt ID:
Q92560

References

  • https://www.degruyter.com/document/doi/10.1515/tjb-2021-0160/html