MAPK8 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-52157-20uL | 20uL | £125.00 |
Quantity:
| E-AB-52157-60uL | 60uL | £172.00 |
Quantity:
| E-AB-52157-120uL | 120uL | £237.00 |
Quantity:
| E-AB-52157-200uL | 200uL | £344.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MAPK8
Background:
MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1,PRKM8,SAPK1,SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73,mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa. This protein can be phosphorylated and this antibody recognizes the 46 kDa and 55 kDa bands in western blot.
Buffer:
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Calculated MW:
48 kDa
Concentration:
1.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:5000, ELISA 1:2000-1:10000
Immunogen:
Fusion protein of human MAPK8
ObservedMW:
Refer to figures
Purification method:
Antigen affinity purification
Target Synonym:
AI849689;c Jun N terminal kinase 1;C-JUN kinase 1;c-Jun N-terminal kinase 1;EC 2.7.11.24;JNK 1;JNK;JNK-46;JNK1A2;JNK21B1/2;MAP kinase 8;MAPK 8;mapk8;Mitogen activated protein kinase 8;Mitogen-activated protein kinase 8;MK08;p54 gamma;Prkm8;Protein kinase JNK1;Protein kinase;mitogen-activated;8;SAPK 1;SAPK gamma;SAPK1;Stress-activated protein kinase 1;Stress-activated protein kinase JNK1
UNIProt ID:
P45983